您的位置:首页 > 产品中心 > Anti-Fmr1 antibody produced in rabbit
Anti-Fmr1 antibody produced in rabbit
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal of human FMR1 |
Biochem/physiol Actions【生化/生理作用】 | Fmr1 is a translation repressor. Fmr1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression. RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.Fmr1 is associated with polysomes. Fmr1 is involved in the transport of mRNA from the nucleus to the cytoplasm. Fmr1 binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C). |
Sequence【序列】 | Synthetic peptide located within the following region: QIGASSRPPPNRTDKEKGYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSES |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 67 kDa |
species reactivity | rat, bovine, rabbit, dog, human, mouse, guinea pig |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_052804 |
UniProt accession no.【UniProt登记号】 | Q80WE1 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... FMR1(2332) rat ... Fmr1(24948) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |