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ANTI-FGF9(N-TERMINAL) antibody produced in rabbit
产品编号: | 3362378 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 400 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
ANTI-FGF9(N-TERMINAL) antibody produced in rabbit
fibroblast growth factor 9
Glia-activating factor
Heparin-binding growth factor 9
FGF9
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 23441 Da |
species reactivity | human, mouse |
technique(s) | flow cytometry: 1:10-1:50 western blot: 1:1000 |
NCBI accession no.【NCBI登记号】 | NP_002001.1 |
UniProt accession no.【UniProt登记号】 | P31371 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... FGF9(2254) |
基本信息
General description【一般描述】 | Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor (GAF) and Heparin-binding growth factor 9 (HBGF-9) belongs to FGF super family. FGF9 was initially purified as a heparin-binding glycoprotein from cultured human glioma cells. FGF9 is widely expressed in epithelial-like and neuronal tissues during embryonic development. In human chromosome, the gene FGF9 is localized on 13q12.11. |
Biochem/physiol Actions【生化/生理作用】 | Fibroblast growth factor 9 (FGF9) is required for lung, heart, inner ear, digestive system and testes development. FGF9 is one of the sex determination genes, expressed in the same pattern in both XX and XY gonads at an early stage, and at later stage, restricted to XY gonads as the testis differentiation proceeds. Fgf9 is essential for mesenchyme proliferation for the lung development and airway branching. Fgf9 along with its receptor Fgfr3 plays a major role in normal skeletal and joint development. Missense mutations in FGF9 leads to multiple synostoses syndrome, characterized by joint fusions, facies and might develop deafness due to fusion of ossicles. |
Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |