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Anti-EXOSC8 (N-terminal) antibody produced in rabbit
产品别名
Anti-EXOSC8 (N-terminal) antibody produced in rabbit
AntiCBP-interacting protein 3
Anit-Exosome component 8,p9
Anti-Rrp43p
Anti-EAP2
Anti-RP11-421P11.3
Anti-OIP2
Anti-Opa interacting protein 2
Anit-CIP3
Anti-Ribosomal RNA-processing protein 43
Anti-RRP43
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~34 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | ~1.0 mg/mL |
| technique(s) | immunoprecipitation (IP): 1-2 μg using human HEK-293T cell lysate western blot: 1-2 μg/mL using whole extracts of mouse A20 and rat PC12 cells |
| UniProt accession no.【UniProt登记号】 | Q96B26 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | bovine ... EXOSC8(532080) dog ... EXOSC8(477300) human ... EXOSC8(11340) mouse ... Exosc8(69639) |
基本信息
| General description【一般描述】 | Exosome component 8 (EXOSC8) or RRP43, a 3′ to 5′ exoribonuclease, is a component of the eukaryotic exosome (a 400 kDa complex). EXOSC8 is part of the hexameric ring, along with EXOSC4-7 and EXOSC9. This is further capped by three RNA binding subunits (EXOSC1-EXOSC3). EXOSC8 gene is mapped to human chromosome 13q13.3 and is localized in nucleus and cytoplasm. |
| Specificity【特异性】 | Anti-EXOSC8 (N-terminal) recognizes human, mouse and rat EXOSC8. |
| Immunogen【免疫原】 | peptide corresponding to the N-terminal region of human EXOSC8, conjugated to KLH. |
| Application【应用】 | Anti-EXOSC8 (N-terminal) antibody produced in rabbit may be used in immunoblotting and immunoprecipitation. |
| Biochem/physiol Actions【生化/生理作用】 | Exosome component 8 (EXOSC8) interacts with AU-rich element (ARE)-containing mRNAs and its deficiency halts growth in yeast. Mutations in the EXOSC8 gene is implicated in Ponto-cerebellar hypoplasia. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide. |
产品说明
| Storage and Stability【储存及稳定性】 | For continuous use, store at 2-8℃ for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
