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Anti-ETS2 antibody produced in rabbit
产品别名
Anti-ETS2 antibody produced in rabbit
Anti-V-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | ETS2 belongs to the Ets family of transcription factors that are crucial mediators of extracellular matrix remodeling. The Ets family members are regulators of bone and cartilage development. |
| Immunogen【免疫原】 | The immunogen for anti-ETS2 antibody: synthetic peptide derected towards the middle region of human ETS2 |
| Application【应用】 | Anti-ETS2 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | ETS family members have binding sites for AP-1 and MAPK proteins. ETS2 significantly regulates the skeletal development and differentiation of osteoblasts. Decreased expression of ETS2 results in skeletal abnormalities similar to those observed in humans with Down′s syndrome. Studies show that ETS2 promotes angiogenesis breast cancer progression. |
| Sequence【序列】 | Synthetic peptide located within the following region: FESFEDDCSQSLCLNKPTMSFKDYIQERSDPVEQGKPVIPAAVLAGFTGS |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 53 kDa |
| species reactivity | mouse, human, guinea pig, rat, dog |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_005230 |
| UniProt accession no.【UniProt登记号】 | P15036 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ETS2(2114) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
