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Anti-EEF2K (N-term) antibody produced in rabbit
| 产品编号： | 3359188 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-EEF2K (N-term) antibody produced in rabbit
Anti-EEF-2K
Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
Anti-EEF-2 kinase
Anti-Elongation factor 2 kinase
Anti-EEF2K
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: 1:1000 western blot: 1:100-1:500 |
| NCBI accession no.【NCBI登记号】 | NP_037434 |
| UniProt accession no.【UniProt登记号】 | O00418 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... EEF2K(29904) |
基本信息
| General description【一般描述】 | Eukaryotic elongation factor 2 kinase (eEF2k) phosphorylates and inactivates eEF2, thereby inhibiting peptide-chain elongation. eEF2k, which is Ca2+ and calmodulin dependent, can be activated by PKA in response to stress-induced elevation of cAMP levels. eEF2k expression is also modulated by a wide range of stimuli that promote cell growth and protein synthesis. Phosphorylation of eEF2k by p90RSK and p70 S6 kinase at Ser366 or by SAPK4/p38d at Ser359, inactivates eEF2k, which facilitates the dephosphorylation of eEF2, and thus promotes translation. |
| Immunogen【免疫原】 | EEF2K (NP_037434, 33-68) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term of human elongation factor 2 kinase. |
| Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
