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Anti-DCP1A (AB1) antibody produced in rabbit
产品别名
Anti-DCP1A (AB1) antibody produced in rabbit
Anti-DCP1 decapping enzyme homolog A (S. cerevisiae)
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 56 kDa |
| species reactivity | rat, human, dog, bovine, guinea pig, rabbit, mouse |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_060873 |
| UniProt accession no.【UniProt登记号】 | Q9NPI6 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... DCP1A(55802) |
基本信息
| General description【一般描述】 | DCP1A is an mRNA decapping enzyme that is involved in TGF-β signaling. DCP1A is known to be hyper-phosphorylated during mitosis, cellular stress, neuronal differentiation and brain development. DCP1A has also been implicated in translational arrest. Rabbit Anti-DCP1A antibody recognizes human, mouse, rat, canine, and bovine DCP1A. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human DCP1A |
| Application【应用】 | Rabbit Anti-DCP1A antibody is suitable for western blot applications at 2.5 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. |
| Sequence【序列】 | Synthetic peptide located within the following region: EEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGD |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
