抗-CEP55 兔抗

HPA023430    Human Protein Atlas characterization data

The gene CEP55 (Centrosomal protein of 55kDa), also referred to as C10orf3, encodes a 464 amino acid containing protein with highest expression in testis and thymus. This coiled-coil protein has a molar mass of 55kDa. The gene is mapped to human chromosome 10q23.33.

centrosomal protein 55kDa recombinant protein epitope signature tag (PrEST)

Anti-CEP55 antibody produced in rabbit has been used in immunohistochemistry.
All Prestige Antibodies^®Powered by Atlas Antibodies is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

The gene CEP55 (Centrosomal protein of 55kDa) encodes a protein that is found to be localized to the mother centriole during interphase. It plays a crucial role in microtubule nucleation, mitotic exit and cytokinesis. The protein CEP55 also elicits the cell transformation by stimulating the phosphatidylinositol 3′-kinase (PI3K)/AKT pathway. It participates in the regulation of cell-cycle and is found in certain tumor tissues, such as hepatocellular carcinoma and gastric cancer. Additionally, it is also involved in midbody structure during cytokinesis.

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

• IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
• Protein array of 364 human recombinant protein fragments.

Corresponding Antigen APREST70314.

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC

rabbit

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

Prestige Antibodies^® Powered by Atlas Antibodies

buffered aqueous glycerol solution

human

antibody small pack of 25 μL

immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:50-1:200
western blot: 0.04-0.4 μg/mL

PLVTFQGETENREKVAASPKSPTAALNESLVECPKCNIQYPATEHRDLLVHVEYCS

Q53EZ4

wet ice

−20℃

human ... CEP55(55165)

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10 - Combustible liquids

WGK 1