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Anti-Centromeric Protein A antibody produced in rabbit
产品别名
Anti-Centromeric Protein A antibody produced in rabbit
CENPA
Centromere protein A
CENA
CENP-A
Centromere autoantigen A
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Centromeric Protein A (CENPA), is encoded by the gene mapped to human chromosome 2p23.3. The encoded protein is a longer variant of histone H3 in humans. Anti-Centromeric protein A Antibody detects endogenous levels of total Centromeric protein A protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Centromeric Protein A. Immunogen Range: 1-50 |
| Biochem/physiol Actions【生化/生理作用】 | Centromeric Protein A (CENPA) plays a vital role in centromere specification and facilitates its mitotic function and epigenetic maintenance. CENP-A-nucleosome associated complex (NAC) is implicated in the regulation of chromosome congression and spindle bipolarity. Disorganization of this complex leads to change in chromosome alignment and segregation that prevent cell survival regardless of continued centromere-derived mitotic checkpoint signaling. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 15 kDa |
| species reactivity | human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 |
| NCBI accession no.【NCBI登记号】 | P49450 |
| UniProt accession no.【UniProt登记号】 | P49450 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CENPA(1058) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
