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Anti-CDX4 (AB2) antibody produced in rabbit

产品编号:3352754
规格:affinity isolated antibody
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3352754100 μL6300
产品别名

Anti-CDX4 (AB2) antibody produced in rabbit

Anti-caudal type homeobox transcription factor 4

基本信息
NACRES
NA.41
General description【一般描述】
Caudal related homeobox (Cdx) genes are known to modulate axial elongation and patterning in many vertebrate embryos. Cdx4 regulates the ontogenesis of placental labyrinth in mice. Furthermore, Cdx4 is known to dysregulate Hox gene expression which causes acute myeloid leukemia in mouse models.
Rabbit Anti-CDX4 (AB2) antibody recognizes rat, mouse, bovine, human, canine, zebrafish, and chicken CDX4.
Immunogen【免疫原】
Synthetic peptide directed towards the middle region of human CDX4
Application【应用】
Rabbit Anti-CDX4 (AB2) antibody is suitable for use in western blot assays at a concentration of 1.0μg/ml. The product can also be used for immunohistochemistry applications at 4-8μg/ml (using paraffin-embedded tissues).
Biochem/physiol Actions【生化/生理作用】
CDX are homeodomain transcription factors related to the Drosophila caudal gene. The vertebrate CDX have been implicated in the development of the posterior embryo. Several signaling molecules, notably retinoic acid (RA) and members of the Wnt (wingless) and fibroblast growth factor (FGF) families, are also implicated in patterning of the posterior vertebrate embryo. CDX family is the target of Wnt, RA and FGF signaling, suggesting that CDX factors act to convey the activity of these signaling molecules to Hox genes.
Sequence【序列】
Synthetic peptide located within the following region: TDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERK
Physical form【外形】
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
30 kDa
species reactivity
human, dog
concentration【浓度】
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_005184
UniProt accession no.【UniProt登记号】
O14627
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... CDX4(1046)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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