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Anti-CDIP antibody produced in rabbit

产品编号:3352568
规格:affinity isolated antibody, buffered aqueous solution, ab2
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3352568100 μG5040
产品别名

Anti-CDIP antibody produced in rabbit

Anti-Cell death involved p53-target

基本信息
NACRES
NA.41
Immunogen【免疫原】
CDIP antibody was raised against a 19 amino acid peptide near the center of human CDIP.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Linkage【联系】
The action of this antibody can be blocked using blocking peptide SBP3500011.
Physical form【外形】
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
产品性质
biological source【生物来源】
rabbit
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
human, mouse
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_037531
UniProt accession no.【UniProt登记号】
Q9H305
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... C16orf5(29965)
产品说明
Target description【目标描述】
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
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