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抗-cdh1 兔抗
Anti-cdh1 antibody produced in rabbit
产品编号: | 3352478 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
抗-cdh1 兔抗
Anti-cdh1 antibody produced in rabbit
CDH1
E-cadherin
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Recombinant protein containing a sequence corresponding to a region within amino acids 499 and 726 of E-cadherin according to |
Application【应用】 | Suggested starting dilutions are as follows: IHC: 1:100-1:1000, IHC-Wm: 1:50-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
Biochem/physiol Actions【生化/生理作用】 | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq] |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | zebrafish |
technique(s) | immunohistochemistry: suitable |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | zebrafish ... cdh1(114424) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H317 - H412 |
Precautionary Statements | P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313 |
Hazard Classifications【危险分类】 | Aquatic Chronic 3 - Skin Sens. 1 |
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |