Anti-CCR5 antibody produced in rabbit

MFCD01864608

NA.41

C-C motif chemokine receptor 5 (CCR5) is expressed by T lymphocytes, macrophages and monocytes. It belongs to the chemokine receptor family. The gene encoding this protein is localized on human chromosome 3p21.31.

a peptide corresponding to amino acids 6-20 of human CCR5.

C-C motif chemokine receptor 5 (CCR5) is a receptor for chemokine ligands-3, -4 and -5. It acts as a co-receptor for human immunodeficiency virus (HIV) entry in cells.The protein also has a role in leukocyte chemotaxis. CCR5 indirectly influence the aggregation of immune cells at the site of viral infection on mucosal surfaces. It also modulates activation of immune cells during inflammation.

The action of this antibody can be blocked using blocking peptide SBP1112.

Solution in phosphate buffered saline containing 0.02% sodium azide

rabbit

unconjugated

IgG fraction of antiserum

primary antibodies

polyclonal

buffered aqueous solution

predicted mol wt 39 kDa

human

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

P51681

dry ice

−20℃

human ... CCR5(1234)

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12 - Non Combustible Liquids

WGK 2