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Anti-C1S (heavy chain, Cleaved-Arg437) antibody produced in rabbit

产品编号:3349480
规格:affinity isolated antibody
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3349480100 μG4610
产品别名

Anti-C1S (heavy chain, Cleaved-Arg437) antibody produced in rabbit

Complement component 1 subcomponent s

C1 esterase

C1S

Complement C1s subcomponent

基本信息
NACRES
NA.41
General description【一般描述】
Anti-C1S (heavy chain, Cleaved-Arg437 Antibody detects endogenous levels of fragment of activated C1S (heavy chain, Cleaved-Arg437protein.
The C1S (complement C1s) gene is mapped to human chromosome 12p13 and codes for a subcomponent of C1 complex of the classical pathway.
Immunogen【免疫原】
The antiserum was produced against synthesized peptide derived from human C1S.

Immunogen Range: 388-437
Biochem/physiol Actions【生化/生理作用】
Activation of C1s (complement C1s) along with C1r triggers complement cascade. C1s is responsible for the cleavage of complement component C4 and C2, which is necessary for complete activation of complement system. Studies determined that C1s specifically acts on Val or Leu at P(3) and Ala or Gly residues at P(2) positions. The C1S gene is known to be associated lupus nephritis, with low gene expression observed in mice.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen 47 kDa
antigen 76 kDa
species reactivity
human
concentration【浓度】
~1 mg/mL
technique(s)
ELISA: 1:20000
western blot: 1:500-1:1000
NCBI accession no.【NCBI登记号】
P09871
UniProt accession no.【UniProt登记号】
P09871
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... C1S(716)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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