Anti-C/EBP-α antibody produced in rabbit

NA.41

CCAAT/enhancer-binding protein α (C/EBPα) is encoded by the gene mapped to human chromosome 19q13.1. The encoded protein belongs to the basic leucine zipper (bZIP) family of transcription factors. CEBPA is highly expressed in differentiated tissues.
Anti-C/EBP-α Antibody detects endogenous levels of total C/EBP-α protein.

The antiserum was produced against synthesized peptide derived from human C/EBP-alpha.

Immunogen Range: 6-55

The transcription factor CCAAT/enhancer-binding protein α (C/EBPα) plays an essential role in tumor progression. It blocks β-catenin to repress lung adenocarcinoma cell invasion and migration. CEBPA is implicated in the regulation of hematopoiesis and terminal differentiation of various cell types like adipocytes, hepatocytes and different epithelial cells. Variations in the gene expression has been observed in 5–10% of cases of acute myeloid leukemia (AML).

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

rabbit

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen 37 kDa

human, rat, mouse

~1 mg/mL

ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

P49715

P49715

wet ice

−20℃

human ... CEBPA(1050)

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12 - Non Combustible Liquids

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