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Anti-C-RAF antibody produced in rabbit
产品别名
Anti-C-RAF antibody produced in rabbit
c-Raf
Protein kinase raf 1
CRAF
kinase Raf1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-C-RAF Antibody detects endogenous levels of total C-RAF protein. Raf-1 proto-oncogene, serine/threonine kinase (RAF1) or C-RAF is an anti-apoptotic protein. The gene encoding it is localized on human chromosome 3p25.2. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human C-RAF. Immunogen Range: 271-320 |
| Biochem/physiol Actions【生化/生理作用】 | Raf-1 proto-oncogene, serine/threonine kinase (RAF1) or C-RAF is a crucial component of the Raf/mitogen-activated extracellular signal-regulated kinase (MEK)/extracellular regulated protein kinase (ERK) signaling cascade. It functions as an activator of MEK-1 and -2. The protein is upregulated in many cancers. Mutations in the gene encoding RAF1 have been linked to Noonan syndrome. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 73 kDa |
| species reactivity | rat, human, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P04049 |
| UniProt accession no.【UniProt登记号】 | P04049 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RAF1(5894) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
