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Anti-BRD2 (AB1) antibody produced in rabbit
产品别名
Anti-BRD2 (AB1) antibody produced in rabbit
Anti-bromodomain containing 2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | BRD2 encodes a transcription factor that is a bromodomain containing protein. Brd2/RING3 is known to associate with the chromatin binding domain of LANA-1 in KSHV (Kaposi′s sarcoma-associated herpesvirus)-infected cells. BRD2 may also be a susceptibility gene for juvenile myoclonic epilepsy. Rabbit Anti-BRD2 (AB2) antibody recognizes human, mouse, rat, canine, zebrafish, chicken, bovine, and pig BRD2. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human BRD2 |
| Application【应用】 | Rabbit Anti-BRD2 is suitable for western blot applications at a concentration of 0.5 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | BRD2 encodes a mitogen-activated kinase which localizes to the nucleus. BRD2 maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human gene may be part of a signal transduction pathway involved in growth control. |
| Sequence【序列】 | Synthetic peptide located within the following region: QEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDD |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 88 kDa |
| species reactivity | rat, horse, human, pig, mouse, dog, bovine |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001106653 |
| UniProt accession no.【UniProt登记号】 | P25440 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BRD2(6046) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
