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Anti-Brachyury 兔抗
Anti-Brachyury antibody produced in rabbit
产品编号: | 3348160 |
规格: | ~1 mg/mL, affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Brachyury 兔抗
Anti-Brachyury antibody produced in rabbit
Anti-Transcription factor T
Anti-T Brachyury, mouse homolog
Anti-T brachyury-like
Anti-T
Anti-TFT
基本信息
NACRES | NA.41 |
General description【一般描述】 | Brachyury (T) is an oncogene mapped to human chromosome 6q27. This gene codes for Brachyury, which is expressed throughout the primary mesoderm during the early stages of embryogenesis. Brachyury protein structure comprises highly conserved DNA binding domain, known as T-box domain. |
Immunogen【免疫原】 | synthetic peptide corresponding to an internal sequence of human brachyury (GeneID 6862). This sequence is 80% identical in mouse and 86% identical in rat. |
Biochem/physiol Actions【生化/生理作用】 | Brachyury protein is a transcription factor that aids in the embryonic development of notochord tissue. It also plays an essential role in posterior mesoderm formation and differentiation. Brachyury is highly expressed in a variety of cancers including, chordoma and hemangioblastoma. It serves as an immunohistochemical marker for differential diagnosis of chordoma and hemangioblastoma (HBL). |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | mouse, human, rat |
concentration【浓度】 | ~1 mg/mL |
technique(s) | immunohistochemistry: 1:100-1:250 western blot: 1:500-1:1,000 |
UniProt accession no.【UniProt登记号】 | O15178 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... T(6862) mouse ... T(20997) rat ... T(292301) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | nwg |