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Anti-BCL-2 Alpha antibody, Rabbit monoclonal
产品编号: | 3347563 |
规格: | clone SP66, recombinant, expressed in proprietary host, affinity isolated antibody |
包装规格: | 100 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
NACRES | NA.41 |
General description【一般描述】 | B-cell lymphoma 2 (BCL-2) is an anti-apoptotic and target gene of nuclear factor-κB (NF-κB). The protein is expressed in the nuclear envelope, mitochondria and endoplasmic reticulum. The gene encoding BCL-2 is localized on human chromosome 18q21. |
Immunogen【免疫原】 | Synthetic peptide corresponding to N-terminus of human BCL-2 alpha protein. |
Biochem/physiol Actions【生化/生理作用】 | B-cell lymphoma 2 (BCL-2) inhibits apoptosis in cells and has been shown to be upregulated in adenomas. Expression of BCL-2α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2α protein, whereas the normal or hyperplastic germinal centers are negative. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | 0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
recombinant【重组】 | expressed in proprietary host |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | SP66, monoclonal |
species reactivity | human (tested) |
technique(s) | flow cytometry: 1:100 immunohistochemistry: 1:100 |
isotype【同位素/亚型】 | IgG |
UniProt accession no.【UniProt登记号】 | P10415 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
Gene Information | human ... BCL2(596) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |