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Anti-ATG3 兔抗

Anti-ATG3 antibody produced in rabbit
产品编号:3346573
规格:affinity isolated antibody, buffered aqueous solution
包装规格:200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3346573200 μL5040
产品别名

Anti-ATG3 兔抗

Anti-ATG3 antibody produced in rabbit

Anti-Autophagy related 3 homolog (S. cerevisiae)

Anti-DKFZp564M1178

Anti-APG3L

Anti-MGC15201

Anti-PC3-96

Anti-APG3

Anti-FLJ22125

基本信息
MDL number
MFCD09753844
General description【一般描述】
Autophagy-related protein 3 (ATG3) is a member of the autophagy-related protein family. It is a mammalian homolog of yeast Apg3p/ Atg3 is ubiquitously expressed in human tissues.
ATG3 is a member of the autophagy-related protein family and is involved in the formation of the autophagosome.
Immunogen【免疫原】
synthetic peptide corresponding to amino acids 17-32 of human Atg3, conjugated to KLH via a C-terminal cysteine residue. The corresponding sequence is identical in rat and mouse.
Application【应用】
Anti-ATG3 antibody produced in rabbit has been used in western blotting and immunoprecipitation.
Biochem/physiol Actions【生化/生理作用】
Autophagy-related protein 3 (ATG3) is involved in the formation of the autophagosome. the mammalian homolog of yeast Apg3p/Aut1p, is an E2-like enzyme that catalyzes the conjugation reaction between Atg8 and phosphatidylethanolamine (PE). Golgi-associated ATPase enhancer of 16 kDa (GATE-16), GABAA receptor-associated protein (GABARAP), and microtubule-associated protein light chain 3 (MAP-LC3) are substrates for Atg3. MAP-LC3 is the preferred substrate. Atg3 interacts with Atg7 to form an E1-E2 complex, and with Atg12, which is a substrate for Atg7 but not for Atg3. Moreover, overexpression of Atg3 facilitates the formation of the Atg12-Atg5 conjugate.
Physical form【外形】
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
200
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen ~36 kDa
species reactivity
rat, human, mouse
technique(s)
immunoprecipitation (IP): 5-10 μL using rat NRK cell lysate
western blot: 2-4 μg/mL using whole extracts of human HeLa and mouse 3T3 cells
UniProt accession no.【UniProt登记号】
Q9NT62
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... ATG3(64422)
mouse ... Atg3(67841)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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