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Anti-ACOT13 antibody produced in mouse

产品编号:3342968
规格:purified immunoglobulin, buffered aqueous solution
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
334296850 μG4610
产品别名

Anti-ACOT13 antibody produced in mouse

HT012

MGC4961

PNAS-27

基本信息
NACRES
NA.41
General description【一般描述】
This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene
Immunogen【免疫原】
ACOT13 (NP_060943.1, 1 a.a. ~ 140 a.a) full-length human protein.

Sequence
MTSMTQSLREVIKAMTKARNFERVLGKITLVSAAPGKVICEMKVEEEHTNAIGTLHGGLTATLVDNISTMALLCTERGAPGVSVDMNITYMSPAKLGEDIVITAHVLKQGKTLAFTSVDLTNKATGKLIAQGRHTKHLGN
Application【应用】
Anti-ACOT13 antibody produced in mouse is suitable for western blot anaysis.
Biochem/physiol Actions【生化/生理作用】
ACOT13 (Acyl-CoA thioesterase 13) is highly involved in the regulation of hepatic lipid and glucose homeostasis. It maintains the intracellular concentration of hepatic free fatty acids (FFAs) and fatty acyl-CoAs under physiological conditions by forming a complex with phosphatidylcholine transfer protein (PC-TP). In liver, it controls the β-oxidation of fatty acids, which is highly crucial for entry of fatty acyl-CoAs into mitochondria.
Physical form【外形】
Solution in phosphate buffered saline, pH 7.4
产品性质
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen ~15 kDa
species reactivity
human
technique(s)
western blot: 1 μg/mL
NCBI accession no.【NCBI登记号】
NM_018473.2
UniProt accession no.【UniProt登记号】
Q9NPJ3
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... ACOT13(55856)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 1
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