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Anti-ARAF antibody produced in rabbit
产品别名
Anti-ARAF antibody produced in rabbit
Anti-ARAF1
Anti-A-RAF
Anti-PKS2
Anti-v-raf murine sarcoma 3611 viral oncogene homolog
Anti-RAFA1
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human ARAF |
| Application【应用】 | Anti-ARAF antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL. |
| Biochem/physiol Actions【生化/生理作用】 | ARAF gene is a proto-oncogene belonging to the RAF subfamily, which encodes cytoplasmic protein serine/threonine kinases. It is localized at human chromosome Xp11.3-p11.23 and is widely expressed in mouse urogenital tissues. It plays a crucial role in cell growth and development. Dimerization of the kinase ARAF facilitates the MAPK activity and cell migration in a cell type-dependent manner. Mutation in ARAF gene causes lung adenocarcinoma associated with sorafenib-sensitive response. |
| Sequence【序列】 | Synthetic peptide located within the following region: PRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYW |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 67 kDa |
| species reactivity | pig, bovine, sheep, mouse, horse, human, rat |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001645 |
| UniProt accession no.【UniProt登记号】 | P10398 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ARAF(369) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
