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Aconitase from porcine heart
产品别名
9024-25-3
Aconitase from porcine heart
Citrate (isocitrate) hydrolyase
Aconitate hydratase
基本信息
| Enzyme Commission (EC) Number【酶学委员会(EC)编号】 | 4.2.1.3 ( BRENDA | IUBMB ) |
| MDL number | MFCD00130335 |
| NACRES | NA.54 |
| Application【应用】 | Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (IRE-BP) and isomerases . |
| Biochem/physiol Actions【生化/生理作用】 | Aconitase catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentrations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity. |
| Unit Definition【单位定义】 | One unit will convert 1.0 μmole of citrate (via cis-aconitate) to isocitrate per min at pH 7.4 at 25 ℃. |
| Analysis Note【分析说明】 | Crude preparation containing aconitase activity |
产品性质
| Quality Level【质量水平】 | 200 |
| form【形式】 | solid |
| mol wt【分子量】 | ~66 kDa by gel filtration |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 150, 250 mg in serum bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
