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8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt
产品别名
276696-61-8
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt
Rp-8-CPT-cGMPS
Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt
Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C16H15ClN5O6PS2 · C6H15N |
Molecular weight | 605.07 |
MDL number | MFCD04037247 |
PubChem Substance ID【PubChem化学物质编号】 | 329775000 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | Rp-8-CPT-cGMP is a potent inhibitor of protein kinase G Ia, Ib, and type II. |
Features and Benefits【特点和优势】 | This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
Linkage【联系】 | 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt is more cell permeable than Rp-cGMPS triethylamine. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | synthetic |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | solid |
color【颜色】 | white |
solubility【溶解性】 | H2O: 5 mg/mL |
storage temp.【储存温度】 | −20℃ |
SMILES string | CCN(CC)CC.NC1=Nc2c(nc(Sc3ccc(Cl)cc3)n2[C@@H]4O[C@@H]5CO[P@@](O)(=S)O[C@H]5[C@H]4O)C(=O)N1 |
InChI | 1S/C16H15ClN5O6PS2.C6H15N/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(27-14)5-26-29(25,30)28-11;1-4-7(5-2)6-3/h1-4,8,10-11,14,23H,5H2,(H,25,30)(H3,18,20,21,24);4-6H2,1-3H3/t8-,10-,11-,14-,29-;/m1./s1 |
InChI key | KVOYZBYGWGWWTD-TXBWCVORSA-N |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |