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(S)-(-)-止呕灵
(S)-(-)-Sulpiride
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3333043 | 5 G | 1320 | |||
| 3333043 | 10 G | 1920 |
产品别名
23672-07-3
(S)-(-)-止呕灵
(S)-(-)-Sulpiride
Levosulpiride
(S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
(S)-5-氨基磺酰基-N-[(1-乙基-2-吡咯烷基)甲基]-2-甲氧基苯甲酰胺
左舒必利
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H23N3O4S |
| Molecular weight | 341.43 |
| MDL number | MFCD00055220 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278709 |
| NACRES | NA.77 |
| Application【应用】 | (S)-(−)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11 |
| Biochem/physiol Actions【生化/生理作用】 | (S)-(−)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function, (S)-(−)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9 D2 多巴胺受体拮抗剂；安定药。 |
| Features and Benefits【特点和优势】 | This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (titration) |
| mp | 183-186 ℃ (lit.) |
| originator【创始人】 | Sanofi Aventis |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O |
| InChI | 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 |
| InChI key | BGRJTUBHPOOWDU-NSHDSACASA-N |
| Gene Information | human ... DRD2(1813), DRD3(1814) rat ... Adra1a(29412), Drd2(24318), Drd3(29238), Htr1a(24473), Htr2a(29595) |
| packaging【包装】 | 5, 10 g in poly bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
