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(R)-3-氨基-1-叔丁氧羰基哌啶

(R)-(-)-3-Amino-1-Boc-piperidine
产品编号:3323810
规格:≥98.0% (TLC)
CAS NO:188111-79-7
包装规格:1G-F
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
33238101G-F1900
产品别名

188111-79-7

(R)-3-氨基-1-叔丁氧羰基哌啶

(R)-(-)-3-Amino-1-Boc-piperidine

(R)-1-Boc-3-piperidinamine

tert-Butyl (R)-3-amino-1-piperidinecarboxylate

(R)-1-Boc-3-氨基哌啶

(R)-1-叔丁氧羰基-3-氨基哌啶

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C10H20N2O2
Molecular weight
200.28
MDL number
MFCD03094717
PubChem Substance ID【PubChem化学物质编号】
329748523
NACRES
NA.22
General description【一般描述】
(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.
Application【应用】
(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98.0% (TLC)
optical activity【旋光性】
[α]/D -28.5±2°, c = 1 in DMF
SMILES string
CC(C)(C)OC(=O)N1CCC[C@@H](N)C1
InChI
1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChI key
AKQXKEBCONUWCL-MRVPVSSYSA-N
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302 - H315 - H319 - H335
Precautionary Statements
P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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