(R)-(+)-氧化苯乙烯

C₈H₈O

120.15

1984

MFCD00066210

24878440

NA.22

Used to produce a homologated epoxide as part of a synthetic approach to (+)-allosedamine.
(R)-(+)-Styrene oxide can be used:

• As a chiral initiator in the synthesis of 5-pyrimidyl alkanol from its corresponding aldehyde using diisopropylzinc.
• As a substrate in the stereoselective intermolecular O-alkylation of phenols with epoxides via Friedel–Crafts-type reaction.
• As a substrate in the ring-opening reactions of epoxides with alcohols, carboxylic acids, and thiols using the AlPW₁₂O₄₀ catalyst.

经 Shasun Chemicals and Drugs Limited 授权，使用 Jacobsen HKR 技术制造。

100

97%

[α]20/D +33°, neat

ee: 97% (GLC)

~22 %

n20/D 1.534 (lit.)

89-90 ℃/23 mmHg (lit.)

1.051 g/mL at 25 ℃ (lit.)

C1O[C@@H]1c2ccccc2

1S/C8H8O/c1-2-4-7(5-3-1)8-6-9-8/h1-5,8H,6H2/t8-/m0/s1

AWMVMTVKBNGEAK-QMMMGPOBSA-N

5 g in glass bottle
25 g in poly bottle

GHS07,GHS08

Danger

H312 - H319 - H350

P202 - P264 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P308 + P313

Acute Tox. 4 Dermal - Carc. 1B - Eye Irrit. 2

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK 3

176.0 °F - closed cup

80 ℃ - closed cup

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter