2-甲氧基-4-硝基苯甲酸

CH₃OC₆H₃(NO₂)CO₂H

197.14

219-998-6

MFCD00216573

24866465

NA.22

2-Methoxy-4-nitrobenzoic acid is an alkoxybenzoic acid derivative. It has been reported to be synthesized by reacting 2-hydroxy-4-nitrobenzoic acid with methyl iodide and characterized by ¹H and ¹³C-NMR spectra.

2-Methoxy-4-nitrobenzoic acid may be used as a starting material in the following syntheses:

• 2-Methoxy-4-nitrobenzamide, a nitroamide derivative.
• 4-Amino-2-methoxybenzamide, an aminobenzamide derivative.
• N,2-Dimethoxy-N-methyl-4-nitrobenzamide, a Weinreb amide derivative.
• 1-(2-Methoxy-4-nitrophenyl)-5-methylhex-2-yn-1-one, a ynone derivative.
• 2,5-Constrained piperidine derivative, a potential CCR3 (Chemokine (C-C Motif) Receptor 3) antagonist.

200

98%

146-148 ℃ (lit.)

COc1cc(ccc1C(O)=O)[N+]([O-])=O

1S/C8H7NO5/c1-14-7-4-5(9(12)13)2-3-6(7)8(10)11/h2-4H,1H3,(H,10,11)

KPJXEWJRJKEOCD-UHFFFAOYSA-N

5 g in glass bottle

GHS07

Warning

H315 - H319 - H335

P302 + P352 - P305 + P351 + P338

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Respiratory system

11 - Combustible Solids

WGK 3

dust mask type N95 (US), Eyeshields, Gloves