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2-氨基-6-甲基巯基嘌呤
2-Amino-6-methylmercaptopurine
产品别名
1198-47-6
2-氨基-6-甲基巯基嘌呤
2-Amino-6-methylmercaptopurine
2-Amino-6-methylthiopurine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C6H7N5S |
| Molecular weight | 181.22 |
| EC number【EC 号】 | 214-833-4 |
| MDL number | MFCD00044701 |
| PubChem Substance ID【PubChem化学物质编号】 | 24891471 |
| NACRES | NA.51 |
| Application【应用】 | 2-Amino-6-methylmercaptopurine is a 2-amino-6-alkyldithiopurine that has been used with other 6-position carbon analogues to study brain specific diazepam binding. 2-Amino-6-methylmercaptopurine (6-MTG) has been used as a supplement in Dulbecco′s modified Eagles medium (DMEM) medium for the selection of gpt-expressing recombinant virus mCMVhMIEPE-gpt.lacZ (cytomegalovirus major immediate-early promotor-enhancer complex-gpt.lacz). It has also been used as a standard in high performance liquid chromatography (HPLC) to assess the activity of thiopurine methyltransferase (TPMT) enzyme. |
| Biochem/physiol Actions【生化/生理作用】 | 2-Amino-6-methylmercaptopurine is synthesized from 6-mercaptopurine by the S methylation activity of thiopurine methyl transferase (TMPT) enzyme. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥95% |
| form【形式】 | solid |
| SMILES string | [H]n1cnc2c(SC)nc(N)nc12 |
| InChI | 1S/C6H7N5S/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11) |
| InChI key | YEGKYFQLKYGHAR-UHFFFAOYSA-N |
| packaging【包装】 | 100 mg in poly bottle |
安全信息
| Pictograms【象形图】 | GHS05,GHS07 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H302 - H315 - H318 - H335 |
| Precautionary Statements | P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
