2-氨基-6-溴苯并噻唑

C₇H₅BrN₂S

229.10

MFCD00152229

24878338

NA.22

Reaction of 4-bromoaniline with acetic acid and potassium thiocynate in solution of bromine in acetic acid yields 2-amino-6-bromobenzothiazole. 2-Amino-6-bromobenzothiazole can also be synthesized from 2-aminobenzothiazole via monobromination with silica-supported quinolinium tribromide.

2-Amino-6-bromobenzothiazole may be used in the synthesis of the following

• 2-amino-6-arylbenzothiazole compounds:
• 6-p-tolylbenzo[d]thiazole-2-amine
• 6-(4chlorophenyl)benzo[d]thiazole-2-amine
• 6-(4-methoxyphenyl)benzo[d]thiazole-2-amine
• 6-(3,5-bis(triflouromethyl)phenyl)benzo[d]thiazole-2-amine
• 6-phenylbenzo[d]thiazole-2-amine

It may be employed as a ligand (L) in the synthesis of organometallic derivatives of Rh(I) [Rh(CO)₂(L)(Cl)].

100

97%

213-217 ℃ (lit.)

Nc1nc2ccc(Br)cc2s1

1S/C7H5BrN2S/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H,(H2,9,10)

VZEBSJIOUMDNLY-UHFFFAOYSA-N

1, 5, 25 g in glass bottle

GHS07

Warning

H302 - H317 - H319

P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1

11 - Combustible Solids

WGK 3

dust mask type N95 (US), Eyeshields, Faceshields, Gloves