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YFLLRNP trifluoroacetate
产品别名
YFLLRNP trifluoroacetate
Tyr-Phe-Leu-Leu-Arg-Asn-Pro
YFLLRNP-OH
L-Tyrosyl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparaginyl-L-Proline
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C45H67N11O10 · xC2HF3O2 |
| Molecular weight | 922.08 (free base basis) |
| MDL number | MFCD16879019 |
| PubChem Substance ID【PubChem化学物质编号】 | 329831587 |
| NACRES | NA.32 |
| Application【应用】 | YFLLRNP trifluoroacetate may be used as a powerful tool for differentiating the numerous possible activation states of the platelet thrombin receptor. |
| Biochem/physiol Actions【生化/生理作用】 | YFLLRNP is a PAR-1-specific partial agonist. The compound selectively activates the G(12/13) signaling cascade resulting in platelet shape. YFLLRNP is a Galpha12/13-stimulating peptide that activates the alpha granule secretion due to costimulation with either ADP or serotonin/epinephrine. |
| Preparation Note【制备说明】 | YFLLRNP trifluoroacetate dissolves in deionized water at 1 mg/mL. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% |
| form【形式】 | solid |
| solubility【溶解性】 | deionized water: 1 mg/mL |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N3CCC[C@H]3C(O)=O |
| InChI | 1S/C45H67N11O10.C2HF3O2/c1-25(2)20-32(40(61)51-31(12-8-18-50-45(48)49)39(60)55-35(24-37(47)58)43(64)56-19-9-13-36(56)44(65)66)53-41(62)33(21-26(3)4)54-42(63)34(23-27-10-6-5-7-11-27)52-38(59)30(46)22-28-14-16-29(57)17-15-28;3-2(4,5)1(6)7/h5-7,10-11,14-17,25-26,30-36,57H,8-9,12-13,18-24,46H2,1-4H3,(H2,47,58)(H,51,61)(H,52,59)(H,53,62)(H,54,63)(H,55,60)(H,65,66)(H4,48,49,50);(H,6,7)/t30-,31-,32-,33-,34-,35-,36-;/m0./s1 |
| InChI key | HMDRRCMAXMJXKF-WDYYMHPRSA-N |
| packaging【包装】 | 1 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
