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WAY-200070

产品编号:3259392
规格:≥98% (HPLC)
CAS NO:440122-66-7
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32593925 MG1860
325939225 MG6750
产品别名

440122-66-7

WAY-200070

7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol

7-bromo-2-(4-hydroxyphenyl)-5-benzoxazolol

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C13H8BrNO3
Molecular weight
306.11
MDL number
MFCD16618385
PubChem Substance ID【PubChem化学物质编号】
329830426
NACRES
NA.77
General description【一般描述】
WAY-200070 is a potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs. 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects.
Application【应用】
WAY-200070, a selective estrogen receptor-beta (ER-β) agonist, may be used in estrogen receptor signaling research along with other ERβ agonists [diarylpropionitrile (DPN)] and antagonist to help identify and differentiate the functions of estrogen receptor-beta(s) (ER-β) involved in processes such as regulation of the physiology of the endocrine pancreas; modulation of visceral pain; and stress response. WAY-200070 may be used to help establish that an observed physiological or cell signaling response is ER-β-dependent, especially versus ERα.
Biochem/physiol Actions【生化/生理作用】
Potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects.
Features and Benefits【特点和优势】
This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
solid
solubility【溶解性】
DMSO: ≥20 mg/mL
originator【创始人】
Wyeth
storage temp.【储存温度】
2-8℃
SMILES string
Oc1ccc(cc1)-c2nc3cc(O)cc(Br)c3o2
InChI
1S/C13H8BrNO3/c14-10-5-9(17)6-11-12(10)18-13(15-11)7-1-3-8(16)4-2-7/h1-6,16-17H
InChI key
BAAILVWEAXFTSF-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H301 - H319
Precautionary Statements
P264 - P270 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313
Hazard Classifications【危险分类】
Acute Tox. 3 Oral - Eye Irrit. 2
Storage Class Code【储存分类代码】
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
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