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WAY-200070
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3259392 | 5 MG | 1860 | |||
3259392 | 25 MG | 6750 |
产品别名
440122-66-7
WAY-200070
7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol
7-bromo-2-(4-hydroxyphenyl)-5-benzoxazolol
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C13H8BrNO3 |
Molecular weight | 306.11 |
MDL number | MFCD16618385 |
PubChem Substance ID【PubChem化学物质编号】 | 329830426 |
NACRES | NA.77 |
General description【一般描述】 | WAY-200070 is a potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs. 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects. |
Application【应用】 | WAY-200070, a selective estrogen receptor-beta (ER-β) agonist, may be used in estrogen receptor signaling research along with other ERβ agonists [diarylpropionitrile (DPN)] and antagonist to help identify and differentiate the functions of estrogen receptor-beta(s) (ER-β) involved in processes such as regulation of the physiology of the endocrine pancreas; modulation of visceral pain; and stress response. WAY-200070 may be used to help establish that an observed physiological or cell signaling response is ER-β-dependent, especially versus ERα. |
Biochem/physiol Actions【生化/生理作用】 | Potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects. |
Features and Benefits【特点和优势】 | This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | solid |
solubility【溶解性】 | DMSO: ≥20 mg/mL |
originator【创始人】 | Wyeth |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | Oc1ccc(cc1)-c2nc3cc(O)cc(Br)c3o2 |
InChI | 1S/C13H8BrNO3/c14-10-5-9(17)6-11-12(10)18-13(15-11)7-1-3-8(16)4-2-7/h1-6,16-17H |
InChI key | BAAILVWEAXFTSF-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 - H319 |
Precautionary Statements | P264 - P270 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Eye Irrit. 2 |
Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 3 |