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尿苷-5′-二磷酸 二钠盐 水合物

Uridine 5′-diphosphate disodium salt hydrate
产品编号:3258092
规格:≥96.0% (HPLC)
CAS NO:27821-45-0
包装规格:100 MG,500 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3258092100 MG1540
3258092500 MG5650
产品别名

27821-45-0

尿苷-5′-二磷酸 二钠盐 水合物

Uridine 5′-diphosphate disodium salt hydrate

5′-UDP-Na2

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C9H12N2Na2O12P2 · xH2O
Molecular weight
448.12 (anhydrous basis)
Beilstein
8817400
EC number【EC 号】
248-678-9
MDL number
MFCD00149253
PubChem Substance ID【PubChem化学物质编号】
57653599
NACRES
NA.51
Application【应用】
Uridine 5′-diphosphate disodium salt hydrate has been used:
  • as a standard for quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC/MS)
  • as a UDP standard for nucleotide analysis by liquid chromatography-high resolution mass spectrometry (LC-HRMS)
  • to treat E6.5 retina explants in vitro, to study its effect on the entry and elongation of microglial cells into the embryonic quail retina

Biochem/physiol Actions【生化/生理作用】
Uridine 5′-diphosphate (UDP) is an endogenous signaling molecule produced by damaged cells to attract macrophages. In response to neuronal damage, UDP promotes chemotaxis and chemokinesis in microglial cells. UDP serves as a ligand for P2Y receptors. UDP and uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled protein receptors (GPCR) and cell signaling molecules such as Rho-signaling via guanine nucleotide exchange factors (GEF).
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
synthetic
Assay【测定】
≥96.0% (HPLC)
form【形式】
powder
impurities【杂质】
≤15% water
storage temp.【储存温度】
−20℃
SMILES string
[Na+].[Na+].[H]O[H].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
InChI
1S/C9H14N2O12P2.2Na.H2O/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t4-,6-,7-,8-;;;/m1.../s1
InChI key
RHBXRWOXLRCWIZ-LLWADOMFSA-L
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H315 - H319 - H335
Precautionary Statements
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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