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Tavaborole

产品编号:3248797
规格:≥95% (HPLC)
CAS NO:174671-46-6
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
324879710 MG1220
324879750 MG4490
产品别名

174671-46-6

Tavaborole

AN-2690

1,3-Dihydro-5-fluoro-1-hydroxy-2,1-benzoxaborole

5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

AN2690

基本信息
Empirical Formula【经验(实验)分子式】
C7H6BFO2
Molecular weight
151.93
NACRES
NA.77
General description【一般描述】
Tavaborole is a boron-based pharmaceutical agent. It has broad-spectrum oxaborole antifungal activity. Due to its low molecular weight, it facilitates maximal nail plate penetration than its predecessors.
Biochem/physiol Actions【生化/生理作用】
Tavaborole (AN2690) is a potent antifungal that targets the post-transfer editing site of leucyl-tRNA synthetase (LeuRS). Tavaborole forms a covalent adduct with the 3′ adenosine of tRNA(leu) at the editing site of fungal, but not bacterial LeuRS, locking the enzyme in an inactive conformation. Tavaborole was recently approved for the treatment of onychomycosis of the toenail in adults.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥95% (HPLC)
form【形式】
powder
storage condition【储存条件】
desiccated
color【颜色】
white to beige
solubility【溶解性】
DMSO: 20 mg/mL, clear
storage temp.【储存温度】
−20℃
packaging【包装】
10, 50 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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