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T56-LIMKi
产品别名
924473-59-6
T56-LIMKi
3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide
T5601640
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H14F3N3O3 |
| Molecular weight | 389.33 |
| MDL number | MFCD08495674 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825772 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | T56-LIMKi is a LIMK2 inhibitor that reduces phosphorylated cofilin, and induces disassembly of actin stress fibers in NF1-/- MEFs cells. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(NC1=CC(C(F)(F)F)=CC=C1)C2=CC(NC(C3=CC(C)=NO3)=O)=CC=C2 |
| InChI | 1S/C19H14F3N3O3/c1-11-8-16(28-25-11)18(27)24-14-6-2-4-12(9-14)17(26)23-15-7-3-5-13(10-15)19(20,21)22/h2-10H,1H3,(H,23,26)(H,24,27) |
| InChI key | XVOKFRPKSAWELK-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 - H413 |
| Precautionary Statements | P273 - P301 + P310 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Aquatic Chronic 4 |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
