您的位置：首页 > 产品中心 > 72741-87-8， 苦马豆素
苦马豆素
Swainsonine
| 产品编号： | 3246166 |
| 规格： | from Metarrhizium anisopliae, ≥98% (TLC) |
| CAS NO： | 72741-87-8 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3246166 | 1 MG | 4420 |
产品别名
72741-87-8
苦马豆素
Swainsonine
(1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol
(1S,2R,8R,8AR)-1,2,8-八氢吲哚啶三醇
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C8H15NO3 |
| Molecular weight | 173.21 |
| Beilstein | 4175740 |
| MDL number | MFCD00017554 |
| PubChem Substance ID【PubChem化学物质编号】 | 24899779 |
| NACRES | NA.85 |
| Application【应用】 | Swainsonine is an indolizidine alkaloid from the plant Metarrhizium anisopliae that is used as a potent α-mannosidase inhibitor. Product S8195 has been used in chemical inhibition assays of CHO Lec2 cells to inhibit glycosylation . 苦马豆素是各种α-甘露糖苷酶的有效抑制剂，特别是α-甘露糖苷酶II。它能够抑制糖蛋白加工，也可作为免疫调节剂。 |
| Biochem/physiol Actions【生化/生理作用】 | Swainsonine is a potent α-mannosidase inhibitor. It also has antimetastatic, antiproliferative, and immunomodulatory activity . It also inhibits glycoprotein processing. |
| Preparation Note【制备说明】 | Soluble in water, methanol, DMSO |
| Other Notes【其他说明】 | Keep container tightly closed in a dry and well-ventilated place. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | Metarrhizium anisopliae |
| Assay【测定】 | ≥98% (TLC) |
| form【形式】 | lyophilized powder |
| storage condition【储存条件】 | (Keep container tightly closed in a dry and well-ventilated place.) |
| color【颜色】 | white to faint yellow |
| solubility【溶解性】 | H2O: soluble 1 mg/mL |
| Mode of action【作用机制】 | enzyme | inhibits |
| antibiotic activity spectrum【抗生素抗菌谱】 | neoplastics |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12 |
| InChI | 1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7?,8-/m1/s1 |
| InChI key | FXUAIOOAOAVCGD-DCDLSZRSSA-N |
| packaging【包装】 | 1MG |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
