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超氧化物歧化酶 来源于牛红细胞

Superoxide Dismutase from bovine erythrocytes
产品编号:3246037
规格:BioUltra, lyophilized powder, ≥4,500 units/mg protein, ≥97% (SDS-PAGE)
CAS NO:9054-89-1
包装规格:15000 UNITS,75000 UNITS
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
324603715000 UNITS2770
324603775000 UNITS10080
产品别名

9054-89-1

超氧化物歧化酶 来源于牛红细胞

Superoxide Dismutase from bovine erythrocytes

Superoxide: superoxide oxidoreductase

SOD

超氧化物:超氧化物氧化还原酶

基本信息
Enzyme Commission (EC) Number【酶学委员会(EC)编号】
1.15.1.1 ( BRENDA | IUBMB )
EC number【EC 号】
232-943-0
MDL number
MFCD00132404
NACRES
NA.54
General description【一般描述】
Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.
Application【应用】
Superoxide Dismutase from bovine erythrocytes has been used in a study to assess activity parameters in adjuvant-induced arthritis. Superoxide Dismutase from bovine erythrocytes has also been used in a study to simplify the process of purifying superoxide dismutases using charge-controlled hydrophobic chromatography on 10-carboxydecyl Sepharose.
Biochem/physiol Actions【生化/生理作用】
催化超氧化物自由基的歧化反应生成过氧化氢和分子氧。在细胞防御氧自由基的毒性作用方面发挥着重要作用。与一氧化氮(NO)竞争超氧化物阴离子(可与NO反应生成过亚硝酸盐),因此SOD能促进NO的活性。在培养的大鼠卵泡、神经细胞系和转基因小鼠中,SOD也表现出抑制细胞凋亡的作用。
Unit Definition【单位定义】
One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25 ℃ in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min.
产品性质
product line【产品线】
BioUltra
Quality Level【质量水平】
200
Assay【测定】
≥97% (SDS-PAGE)
form【形式】
lyophilized powder
Specific Activity
≥4,500 units/mg protein
mol wt【分子量】
32.5 kDa
composition【组成】
Protein, ≥95% biuret
relevant disease(s)【相关疾病】
arthritis
storage temp.【储存温度】
−20℃
packaging【包装】
15000, 75000 units in glass bottle
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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