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超肉桂醛
Supercinnamaldehyde
产品别名
70351-51-8
超肉桂醛
Supercinnamaldehyde
1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H11NO2 |
| Molecular weight | 201.22 |
| MDL number | MFCD08530327 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824530 |
| NACRES | NA.77 |
| Application【应用】 | Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC50 = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway. |
| Caution【注意】 | Air-sensitive |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | faintly red to very dark red |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN1C(=O)C(=C\C(C)=O)\c2ccccc12 |
| InChI | 1S/C12H11NO2/c1-8(14)7-10-9-5-3-4-6-11(9)13(2)12(10)15/h3-7H,1-2H3/b10-7+ |
| InChI key | CZKBLHCEDVWPRN-JXMROGBWSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
