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硫前列酮
Sulprostone
产品别名
60325-46-4
硫前列酮
Sulprostone
SHB-286
CP-34089
(5Z,11α,13E,15R)--11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide
ZK-57671
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H31NO7S |
| Molecular weight | 465.56 |
| EC number【EC 号】 | 262-173-0 |
| MDL number | MFCD00216056 |
| PubChem Substance ID【PubChem化学物质编号】 | 24724621 |
| NACRES | NA.77 |
| Application【应用】 | Human chondrocytes3 and mouse adrenal chromaffin cells4 were treated with sulprostone to study the biological effects of PGE2. |
| Biochem/physiol Actions【生化/生理作用】 | Sulprostone is an analog of prostaglandin E2 (PGE2)1 and antagonizes vasopressin-induced antidiuretic responses in cells from rat renal inner medullae by a mechanism that involves activation of Rho.2 Selective EP3 prostanoid receptor agonist. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | oil |
| color【颜色】 | colorless to yellow-brown |
| solubility【溶解性】 | DMSO: >10 mg/mL |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CS(=O)(=O)NC(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\[C@@H](O)COc2ccccc2)[C@H](O)CC1=O |
| InChI | 1S/C23H31NO7S/c1-32(29,30)24-23(28)12-8-3-2-7-11-19-20(22(27)15-21(19)26)14-13-17(25)16-31-18-9-5-4-6-10-18/h2,4-7,9-10,13-14,17,19-20,22,25,27H,3,8,11-12,15-16H2,1H3,(H,24,28)/b7-2-,14-13+/t17-,19-,20-,22-/m1/s1 |
| InChI key | UQZVCDCIMBLVNR-TWYODKAFSA-N |
| packaging【包装】 | 1, 5 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H315 - H319 - H335 - H360 |
| Precautionary Statements | P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
