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SMER28

产品编号:3240494
规格:>99% (HPLC), solid
CAS NO:307538-42-7
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32404945 MG1800
324049425 MG7400
产品别名

307538-42-7

SMER28

6-Bromo-N-2-propenyl-4-quinazolinamine

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C11H10BrN3
Molecular weight
264.12
MDL number
MFCD02166825
PubChem Substance ID【PubChem化学物质编号】
329824598
NACRES
NA.77
Application【应用】
SMER28 may be used in mTOR-mediated signaling studies.
Biochem/physiol Actions【生化/生理作用】
SMER28 is a small molecule modulator of mammalian autophagy; enhances A53T alpha-synuclein clearance in PC-12 cells independent of rapamycin treatment; appears to act independent of the mTOR pathway, but combined treatment with saturating rapamycin concentration enhances the effect of either compound alone on A53T alpha-synuclein clearance; autophagy inducers may prove useful in the treatment of neurodegenerative and infectious diseases and cancer.
产品性质
Quality Level【质量水平】
100
Assay【测定】
>99% (HPLC)
form【形式】
solid
solubility【溶解性】
DMSO: >20 mg/mL
H2O: insoluble
storage temp.【储存温度】
2-8℃
SMILES string
Brc1ccc2ncnc(NCC=C)c2c1
InChI
1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15)
InChI key
BCPOLXUSCUFDGE-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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