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[6]-姜烯酚
Shogaol
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3218494 | 50 MG | 9200 |
产品别名
555-66-8
[6]-姜烯酚
Shogaol
[6]-Shogaol
(6)-Shogaol
1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one
1-(4-羟基-3-甲氧基苯基)癸-4-烯-3-酮
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C17H24O3 |
Molecular weight | 276.37 |
Beilstein | 2056098 |
MDL number | MFCD01736094 |
PubChem Substance ID【PubChem化学物质编号】 | 329824943 |
NACRES | NA.25 |
General description【一般描述】 | Shogaol or 6-shogaol, the pungent metabolite of dried ginger, is one of the main bioactive compounds extracted from the natural dietary rhizome, Zingiber officinale Roscoe (ginger). It is the dehydrated successor of 6-gingerol with an α,β-unsaturated ketone skeleton. |
Application【应用】 | Shogaol has been used to determine its safe dose to evaluate potential toxicity in higher concentrations in mice models. It has also been used to investigate its antioxidant effects on the modulation of TRPC5 (ITRPC5) and TRPA1 (ITRPA1) currents. |
Biochem/physiol Actions【生化/生理作用】 | Shogaols exhibits higher potency, efficacy, and biological activities than gingerols. It is an excellent antioxidant agent, that protects human primary epidermal melanocytes against oxidative stress by activating nuclear factor E2-related factor (Nrf2)-antioxidant response. Shogaol also displays antimicrobial, antifungal, and anti-biofilm activities against Candida albicans, and Candida auris. It exerts anti-inflammatory properties and protects against abdomen irradiation (ABI)-induced intestinal side effects. 6-shogaol also inhibits lipopolysaccharide (LPS)-induced inflammation via peroxisome proliferator-activated receptor gamma (PPAR-γ) activation. |
产品性质
Assay【测定】 | ≥90% (HPLC) |
form【形式】 | liquid |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | CCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1 |
InChI | 1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+ |
InChI key | OQWKEEOHDMUXEO-BQYQJAHWSA-N |
packaging【包装】 | 50 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |