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SB 222200
| 产品编号： | 3216982 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 174635-69-9 |
| 包装规格： | 10 MG，50 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
174635-69-9
SB 222200
(S)-3-Methyl-2-phenyl-N-(1-phenylpropyl)-4-quinolinecarboxamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C26H24N2O |
| Molecular weight | 380.48 |
| MDL number | MFCD00944072 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278254 |
| NACRES | NA.77 |
| Application【应用】 | The pharmacodynamics profile of SB 222200 enables its use as a tool to study physiological and pathophysiological roles of NK-3 receptor in CNS-modulated behaviors. |
| Biochem/physiol Actions【生化/生理作用】 | SB 222200 is a 2-phenyl-4-quinolinecarboxamides and a selective, reversible and competitive antagonist of human NK-3 receptor that effectively crosses the blood-brain barrier. It inhibits the NK-3 receptor-induced miosis or pupil constriction in conscious rabbits.1,2 Non-peptide NK3 tachykinin receptor antagonist. |
| Features and Benefits【特点和优势】 | This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Sold for research purposes under agreement from GlaxoSmithKline |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | light yellow |
| solubility【溶解性】 | DMSO: soluble ~28 mg/mL H2O: insoluble |
| originator【创始人】 | GlaxoSmithKline |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC[C@H](NC(=O)c1c(C)c(nc2ccccc12)-c3ccccc3)c4ccccc4 |
| InChI | 1S/C26H24N2O/c1-3-22(19-12-6-4-7-13-19)28-26(29)24-18(2)25(20-14-8-5-9-15-20)27-23-17-11-10-16-21(23)24/h4-17,22H,3H2,1-2H3,(H,28,29)/t22-/m0/s1 |
| InChI key | MQNYRKWJSMQECI-QFIPXVFZSA-N |
| Gene Information | human ... TACR2(6865), TACR3(6870) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
