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S-(+)-Chlorpheniramine maleate salt
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3216088 | 1 G | 1360 | |||
3216088 | 5 G | 3920 |
产品别名
2438-32-6
S-(+)-Chlorpheniramine maleate salt
(S)-γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine maleate salt
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C16H19ClN2 · C4H4O4 |
Molecular weight | 390.86 |
EC number【EC 号】 | 219-450-6 |
MDL number | MFCD00079046 |
PubChem Substance ID【PubChem化学物质编号】 | 24278317 |
NACRES | NA.77 |
General description【一般描述】 | Chlorpheniramine maleate is a cationic amphiphilic anti-histamine agent, which is composed of a hydrophobic ring structure and a hydrophilic side chain with a charged cationic amino group. |
Application【应用】 | S-(+)-Chlorpheniramine maleate salt has been used to study the anticholinergic effect of Achillea millefolium and Portulaca olerace on muscarinic receptors of guinea pig tracheal smooth muscle. |
Biochem/physiol Actions【生化/生理作用】 | H1 histamine receptor antagonist; active isomer. Chlorpheniramine maleate is clinically used as a topical ointment to treat skin disorders such as sunburn, urticaria, angioedema, pruritus and insect bites. |
Features and Benefits【特点和优势】 | This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
Quality Level【质量水平】 | 200 |
originator【创始人】 | Bayer |
SMILES string | [H]\C(=C(/[H])C(O)=O)C(O)=O.CN(C)CC[C@@H](c1ccc(Cl)cc1)c2ccccn2 |
InChI | 1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1 |
InChI key | DBAKFASWICGISY-DASCVMRKSA-N |
Gene Information | human ... HRH1(3269) |
packaging【包装】 | 1, 5 g in glass bottle |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 |
Precautionary Statements | P301 + P310 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |