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S-(+)-Chlorpheniramine maleate salt

产品编号:3216088
CAS NO:2438-32-6
包装规格:1 G,5 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32160881 G1360
32160885 G3920
产品别名

2438-32-6

S-(+)-Chlorpheniramine maleate salt

(S)-γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine maleate salt

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C16H19ClN2 · C4H4O4
Molecular weight
390.86
EC number【EC 号】
219-450-6
MDL number
MFCD00079046
PubChem Substance ID【PubChem化学物质编号】
24278317
NACRES
NA.77
General description【一般描述】
Chlorpheniramine maleate is a cationic amphiphilic anti-histamine agent, which is composed of a hydrophobic ring structure and a hydrophilic side chain with a charged cationic amino group.
Application【应用】
S-(+)-Chlorpheniramine maleate salt has been used to study the anticholinergic effect of Achillea millefolium and Portulaca olerace on muscarinic receptors of guinea pig tracheal smooth muscle.
Biochem/physiol Actions【生化/生理作用】
H1 histamine receptor antagonist; active isomer.
Chlorpheniramine maleate is clinically used as a topical ointment to treat skin disorders such as sunburn, urticaria, angioedema, pruritus and insect bites.
Features and Benefits【特点和优势】
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
产品性质
Quality Level【质量水平】
200
originator【创始人】
Bayer
SMILES string
[H]\C(=C(/[H])C(O)=O)C(O)=O.CN(C)CC[C@@H](c1ccc(Cl)cc1)c2ccccn2
InChI
1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1
InChI key
DBAKFASWICGISY-DASCVMRKSA-N
Gene Information
human ... HRH1(3269)
packaging【包装】
1, 5 g in glass bottle
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H301
Precautionary Statements
P301 + P310
Hazard Classifications【危险分类】
Acute Tox. 3 Oral
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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