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Ro 61-8048

产品编号:3215601
规格:≥98% (HPLC)
CAS NO:199666-03-0
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
32156015 MG1770
321560125 MG4930
产品别名

199666-03-0

Ro 61-8048

3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-benzenesulfonamide

Ro-61-8048

3,4-Dimethoxy-N-[4-(3-nitrophenyl)thiazol-2-yl]benzenesulfonamide

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C17H15N3O6S2
Molecular weight
421.45
MDL number
MFCD11040807
PubChem Substance ID【PubChem化学物质编号】
329825246
Application【应用】
Ro 61-8048 has been used as a kynurenine 3-monooxygenase (KMO) inhibitor to study its effects on nicotinamide adenine dinucleotide (NAD+) concentration in hepatocytes of mice.
Biochem/physiol Actions【生化/生理作用】
Ro 61-8048 is an inhibitor of kynurenine 3-monooxygenase (KMO) that increases kynurenic acid levels and reduces extracellular glutamate in the brain.
Inhibition of kynurenine 3-hydroxylase by Ro 61-8048 reduces the episodes of dystonia and dyskinesias induced by decreased levels of kynurenic acid.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
faintly yellow to yellow
solubility【溶解性】
DMSO: ≥15 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
COc1ccc(cc1OC)S(=O)(=O)Nc2nc(cs2)-c3cccc(c3)[N+]([O-])=O
InChI
1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
InChI key
NDPBMCKQJOZAQX-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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