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Resistin from rat
| 产品编号： | 3214972 |
| 规格： | recombinant, expressed in E. coli, ≥95% (SDS-PAGE) |
| 包装规格： | 25 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Resistin from rat
Adipose tissue-specific secretory factor
RSTN
Cysteine-rich secreted protein A12-α-like 2
ADSF
C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein
Cysteine-rich secreted protein FIZZ3
基本信息
| MDL number | MFCD03792461 |
| NACRES | NA.32 |
| General description【一般描述】 | Resistin is a new member to of the family of adipocyte-secreted proteins. The biological functions of resistin, as well as its molecular target, are largely unknown. Whether it promotes or antagonizes insulin action is still unclear. Recombinant rat Resistin is an 11.9 kDa protein consisting of 94 amino acid residues and 16 additional amino acids residues-His Tag. Resistin is an adipocytokine secreted by fat tissues and is localized to pancreatic α-cells in rat. |
| Application【应用】 | Resistin from rat has been used to study the effect of resistin on gonadotropins and local ovarian hormone-induced steroidogenesis. |
| Biochem/physiol Actions【生化/生理作用】 | Resistin mediates energy homeostasis and inflammation process. Upregulation of resistin is observed in obesity. It is also known to increase blood glucose level and might promote insulin resistance. Thus, it might influence type 2 diabetes. Resistin might be linked to insulin resistance mediated myocardial infarction (MI). In rats, overexpression of resistin is observed in myocardial infarction and cardiac dysfunction. |
| Physical form【外形】 | Lyophilized from 20 mM Tris, pH 8.0. |
| Reconstitution【重悬】 | Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers. Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
产品性质
| biological source【生物来源】 | rat |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~11.9 kDa |
| packaging【包装】 | pkg of 25 μg |
| impurities【杂质】 | endotoxin, tested |
| NCBI accession no.【NCBI登记号】 | NP_653342 |
| UniProt accession no.【UniProt登记号】 | Q8CJE0 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | rat ... Retn(246250) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
