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Rabbit anti-MSH2 Antibody, Affinity Purified
产品别名
Rabbit anti-MSH2 Antibody, Affinity Purified
FCC1
mutS homolog 2
LCFS2
COCA1
MutS protein homolog 2
HNPCC
nonpolyposis type 1
nonpolyposis type 1 (E. coli)
HNPCC1
mutS (E. coli) homolog 2 (colon cancer; nonpolyposis type 1)
colon cancer
hMSH2
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | The epitope recognized by PLA0106 maps to a region between residues 1 and 50 of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246 (GeneID 4436). |
| Physical form【外形】 | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide |
| Other Notes【其他说明】 | MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC). |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human, mouse |
| technique(s) | immunoprecipitation (IP): 2-10 μg/mg western blot: 1:1,000-1:5,000 |
| accession no.【登记号】 | P43246 |
| UniProt accession no.【UniProt登记号】 | P43246 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | rabbit ... MSH2(4436) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
