Protein L–Agarose from Peptostreptococcus magnus

NA.56

Protein L from Peptostreptococcus magnus binds immunoglobulins (Ig) primarily through kappa light chain interactions without interfering with the antigen binding site. Recombinant Protein L contains four Ig-binding domains.
Protein L-agarose is used in affinity chromatography, protein chromatography, antibody purification and characterization, immunoaffinity matrices, phosphorylation analysis, and protein A, G and L resins. Protein L-agarose has been used to provide evidence that antineuronal antibodies may contribute to neuronal dysfunction observed in a subset of patients with neurogenic chronic intestinal pseudoobstruction. Protein L agarose has also been used to evaluate a diabody to improve protection againse a potent scorpion neurotoxin.

Prepared with recombinant Peptostreptococcus magnus Protein L.

200

expressed in E. coli

6% beaded agarose supplied as 50% slurry

cyanogen bromide

amino

3-10 mg/mL binding capacity

2-8℃

5 mL in glass bottle

12 - Non Combustible Liquids

WGK 3