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Prosaptide Tx 14(A) trifluoroacetate salt
产品别名
196391-82-9
Prosaptide Tx 14(A) trifluoroacetate salt
TaLIDNNATEEILY trifluoroacetate salt
TX14(A) trifluoroacetate salt
Prosaptide trifluoroacetate salt
TXLIDNNATEEILY (Modifications: Ala-2 = D-Ala) trifluoroacetate salt
H-Thr-D-Ala-Leu-Ile-Asp-Asn-Asn-Ala-Thr-Glu-Glu-Ile-Leu-Tyr-OH trifluoroacetate salt
基本信息
| Empirical Formula【经验(实验)分子式】 | C69H110N16O26 · xC2HF3O2 |
| Molecular weight | 1579.70 (free base basis) |
| Biochem/physiol Actions【生化/生理作用】 | Prosaptide Tx 14(A) is a potent agonist of G protein-coupled receptors GPR37 (also known as Parkin-associated endothelin receptor-like receptor Pael-R) and GPR37L1. Prosaptide Tx 14(A) is the active fragment of prosaposin, a secreted neuroprotective and glioprotective factor. Prosaptide Tx 14(A) has EC50 values of 5 nM for GPR37L1 and 7 nM for GPR37, and has also been shown to have some GSK3 inhibitory properties. Prosaptide has been shown to improve nerve regeneration in diabetic rats, to reduce neuropathic pain, and to protect dopaminergic neurons in animal models of Parkinson disease. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to off-white |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 1 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
