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Poly(D,L -lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(D,L -lactide-co-glycolide) based poly(ether ester urethane)
产品别名
Poly(
poly(ester ether urethane)
PLGA-PEG-PLGA urethane
PEEU
VISCOPRENE 9
结构式
基本信息
| Linear Formula【线性分子式】 | [C2H2N2O2R[(C3H4O2)x(C2H2O2)y]m[C2H4O]lO[(C3H4O2)x(C2H2O2)y]m]n |
| PubChem Substance ID【PubChem化学物质编号】 | 329768204 |
| NACRES | NA.23 |
| Application【应用】 | This poly(ether ester urethane) based on PLGA-PEG-PLGA triblock copolymers linked with a diisocyanate is a biodegradable, resorbable gel former for use in drug delivery systems. This polymer doesn′t rely on temperature or pH to induce gelation, and therefore forms more consistent and faster-setting drug delivery depots. Through combination of various gel formers and/or diluents, drug release profiles may be modulated to exhibit fast burst release through extended (up to 1 month) zero-order release profile. Mass loss of the resultant drug delivery depots is complete within 4 months. |
| Legal Information【法律信息】 | Product of Poly-Med, Inc. VISCOPRENE® is a registered trademark of Poly-Med, Inc. Viscoprene is a registered trademark of Poly-Med, Inc. |
产品性质
| Quality Level【质量水平】 | 100 |
| form【形式】 | amorphous solid |
| feed ratio【投料比】 | 13:(70:17) (PEG:( lactide:glycolide 80:20 |
| mol wt【分子量】 | PEG average Mn 400 average Mn (6,000-15,000) |
| degradation timeframe【降解时间线】 | <4 months |
| transition temp【转变温度】 | Tg <0 ℃ |
| PDI | <2.0 |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC(N[R]NC(OC(C)C(OCC(OCCOC(C(C)OC(COC)=O)=O)=O)=O)=O)=O.CC(N[R]NC(OCCCOC)=O)=O |
| packaging【包装】 | 1, 5 g in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
