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Plasminogen Activator Substrate
基本信息
| Empirical Formula【经验(实验)分子式】 | C28H41N7O5 |
| Molecular weight | 555.67 |
| NACRES | NA.32 |
| Amino Acid Sequence | BOC-Val-Gly-Arg-βNA |
| Application【应用】 | Plasminogen Activator Substrate has been used as a fluorogenic thrombin substrate to measure the fluorescence released by cleavage of the thrombin substrate to assess the functional activity of the mannose-binding lectin–mannose-associated serine protease (MBL-MASP) complex. Plasminogen Activator is a serine protease that coverts plasminogen into plasmin. Plasminogen activator may be detected using VGR peptide substrates such a BOC-VGR-βNA and Boc-Val-Gly-Arg-AMC (VGR). |
| Biochem/physiol Actions【生化/生理作用】 | Plasminogen activator (PA) is used to cure life-threatening coronary and cerebrovascular blockages. The important role of the PA system is to convert the inactive plasminogen to plasmin. However, it also plays a vital role in embryogenesis, cell migration, wound healing, inflammatory response, and apoptotic cell death. The PA system is also involved in tumor growth, angiogenesis, tumor cell invasion, migration, and metastasis in cancer patients. |
产品性质
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | lyophilized |
| composition【组成】 | Peptide Content, ≥80% |
| storage condition【储存条件】 | protect from light |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
