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酚妥拉明
Phentolamine Mesylate
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3180997 | 1 G | 1760 |
产品别名
65-28-1
酚妥拉明
Phentolamine Mesylate
2-(N-[m-Hydroxyphenyl]-p-toluidinomethyl)imidazoline
Phentolamine methanesulfonate salt
酚妥拉明 甲磺酸盐
2-(N-[m-羟基苯基]-p-甲苯氨基甲基)咪唑啉
结构式
基本信息
Linear Formula【线性分子式】 | C17H19N3O · CH3SO3H |
Molecular weight | 377.46 |
EC number【EC 号】 | 200-604-6 |
MDL number | MFCD00134201 |
PubChem Substance ID【PubChem化学物质编号】 | 329823376 |
NACRES | NA.24 |
General description【一般描述】 | Phentolamine Mesylate belongs to the class of alpha adrenergic antagonist drugs. It is used in the treatment of pheochromocytoma-related hypertension, erectile dysfunction and in the diagnosis of pheochromocytoma and norepinephrine-related dermal necrosis. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
Application【应用】 | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Phentolamine Mesylate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chemiluminescence technique. |
Biochem/physiol Actions【生化/生理作用】 | α-肾上腺素受体拮抗剂;外周血管舒张剂。 |
Analysis Note【分析说明】 | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Other Notes【其他说明】 | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Footnote【附注】 | To see an example of a Certificate of Analysis for this material enter LRAC3261 in the slot below. This is an example certificate only and may not be the lot that you receive. |
产品性质
Quality Level【质量水平】 | 300 |
grade【等级】 | certified reference material pharmaceutical secondary standard |
CofA | current certificate can be downloaded |
technique(s) | HPLC: suitable gas chromatography (GC): suitable |
mp | 180-182 ℃ (lit.) |
application(s) | pharmaceutical (small molecule) |
format【格式】 | neat |
pharmacopeia traceability【药典可追溯性】 | traceable to PhEur Y0001127 traceable to USP 1530004 |
storage temp.【储存温度】 | 2-30℃ |
SMILES string | CS(O)(=O)=O.Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3 |
InChI | 1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4) |
InChI key | OGIYDFVHFQEFKQ-UHFFFAOYSA-N |
Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152) |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 - H315 - H319 - H335 |
Precautionary Statements | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
Target Organs【靶器官】 | Respiratory system |
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |